Search peptides — top sellers first
Search peptides — top sellers first
Search peptides — top sellers first
L-Alpha-GPC for acetylcholine synthesis, cognitive function, and short-duration power output.
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Alpha-GPC · mg
Frequently bought together
Researchers usually add these to complete the protocol.
Zinc Bisglycinate · mg
Popular · Foundation
Vitamin C · mg
Foundation
L-Theanine · mg
Recovery
Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Vantage Analytical
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Purity
Know your compound
Alpha-GPC is a choline compound found naturally in cell membranes and in small amounts in foods like organ meats and dairy. It crosses the blood-brain barrier efficiently and serves as a substrate the body uses to make acetylcholine, the neurotransmitter tied to attention, learning, and muscle activation. It also supplies choline for phosphatidylcholine, a structural building block of every cell membrane. Supplementation is discussed because Alpha-GPC delivers choline more efficiently than most dietary sources.
A 2023 meta-analysis of adult-onset cognitive dysfunction found choline alphoscerate associated with measurable cognitive improvement across pooled trials. Most of that signal comes from older adults and from populations with existing impairment, not from healthy young people. The power-output work is separate, smaller, and early: a handful of sports-science trials, worth reading as preliminary.
For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
Published research on the reference compound class. Provided for scientific context only — not a claim about the product supplied.
In a 2023 meta-analysis of adults with age-related cognitive decline, choline alphoscerate was associated with measurable improvement in cognitive test scores — the signal was strongest in older and impaired adults and thinner in healthy young people.
Directional pooled effect; strongest in older/impaired adults.
A handful of small sports-science trials looked at short-duration power output during training and pointed in a favorable direction — but samples were small and the results should be read as preliminary.
Directional only — small samples, no pooled magnitude.
In a rodent model, late α-GPC treatment increased new cell growth in the hippocampus and protected against neuronal loss — an animal-only finding that does not translate directly to people.
Preclinical rodent seizure model; directional.
Mechanism
Alpha-GPC is studied to act through three distinct routes tied to choline delivery and membrane biology.
Alpha-GPC supplies choline that the body uses as a substrate for acetylcholine, the neurotransmitter involved in attention, learning, and muscle activation.
It contributes choline to phosphatidylcholine, a structural phospholipid found in every cell membrane.
Its transport efficiency across the blood-brain barrier is the main reason it is studied more than other choline sources.
For research use only. Mechanisms described reflect published preclinical and clinical literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
Best sellers
FAQ
Common questions about Alpha-GPC
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
Order with coverThird-party tested
An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.
