In rats, magnesium compounds were absorbed at different rates in a dose-dependent way — which is why the specific form on the label matters, not just the milligrams.
Absorption rose with dose; profiles differed by compound.
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Chelated magnesium bisglycinate for muscle function, nervous system support, and sleep quality.
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Magnesium Glycinate · mg
Frequently bought together
Researchers usually add these to complete the protocol.

Zinc Bisglycinate · mg
Popular · Foundation

Vitamin C · mg
Foundation

L-Theanine · mg
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Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Vantage Analytical
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Purity
Know your compound
Magnesium is a mineral that acts as a cofactor in more than 300 enzymatic reactions, including every reaction that uses or makes ATP, your cells' energy currency. Most of your supply sits in bone and muscle, and dietary intake in the US commonly falls below the recommended amount. This form binds magnesium to glycine, an amino acid, in a chelate — a stable pairing chosen because it absorbs well and is gentler on the gut than oxide or citrate.
A dose-comparison study found different magnesium compounds absorb at different rates, which is why the specific form on the label matters. Researchers study magnesium repletion mostly in people with low intake, where effects on muscle and sleep measures are more consistent. The evidence is weaker in people already replete — a real limit, and the reason this sits as a foundation product, not a fix.
For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
Published research on the reference compound class. Provided for scientific context only — not a claim about the product supplied.
In rats, magnesium compounds were absorbed at different rates in a dose-dependent way — which is why the specific form on the label matters, not just the milligrams.
Absorption rose with dose; profiles differed by compound.
In a randomized double-blind trial in adults, magnesium was studied alongside vitamin D for its effect on vitamin D status, inflammation and blood pressure.
Endpoints were vitamin D status, inflammation and blood pressure; magnitudes not quantified here.
In the same adult trial, combined magnesium and vitamin D did not measurably change markers of bone turnover or blood-sugar control — an honest null result worth reporting.
No significant influence detected on either marker set.
In male Wistar rats, chronic magnesium glycinate shifted measures of intestinal motility along with food and water intake versus baseline.
Directional change in ileum motility; exact magnitude not quantified here.

Mechanism
Magnesium is studied to act through three distinct routes in the body, each tied to its role as an enzymatic cofactor.
Magnesium is required for every enzymatic reaction that uses or produces ATP, the molecule cells rely on for energy.
Magnesium is involved in the ion signaling that governs muscle contraction and relaxation and normal nerve conduction.
The glycine bound to magnesium is itself studied for a role in sleep onset, so this chelate contributes two studied molecules.
For research use only. Mechanisms described reflect published preclinical and clinical literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
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FAQ
Common questions about Magnesium Glycinate
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
Order with coverThird-party tested
An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.