Search peptides — top sellers first
Search peptides — top sellers first
Search peptides — top sellers first
Magnesium L-threonate for cognitive function, sleep depth, and nervous system support.
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Magnesium L-Threonate · mg
Frequently bought together
Researchers usually add these to complete the protocol.
Zinc Bisglycinate · mg
Popular · Foundation
Vitamin C · mg
Foundation
L-Theanine · mg
Recovery
Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Vantage Analytical
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Purity
Know your compound
Magnesium L-threonate binds elemental magnesium to threonic acid, a metabolite of vitamin C. Magnesium is a mineral your body uses in hundreds of enzyme reactions, and in the brain it sits in the NMDA receptor, a gate that controls how nerve cells signal each other. This form was built because most magnesium salts raise magnesium in the blood without meaningfully changing it in cerebrospinal fluid, the liquid bathing the brain and spine.
In aged rats, raising brain magnesium was linked to greater synaptic density and better performance on memory tasks — the 2010 result that put this form on the map. Human trials exist but are small and short, and this is the least-settled product in our lineup. We would rather say that than imply the rodent data transfers cleanly to people.
For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
Published research on the reference compound class. Provided for scientific context only — not a claim about the product supplied.
In a small, short trial in healthy Chinese adults, a Magtein-based magnesium L-threonate formula was associated with improved cognitive measures versus control — early human data that has not yet been confirmed in larger, longer studies.
Directional result — the trial reported improvement but the effect size is not shown here.
In aged and young rats, raising brain magnesium was linked to greater synaptic density and better memory-task performance — the foundational 2010 finding, in animals only.
Directional: synaptic density and memory performance rose; magnitudes not quantified here.
In mice, oral magnesium L-threonate raised magnesium levels in the cerebrospinal fluid — evidence, in animals, that this form can reach the fluid around the brain.
Directional rise in CSF magnesium; exact concentrations not shown.
Mechanism
Magnesium L-threonate is studied to act through three distinct routes in the nervous system.
Magnesium modulates activity at NMDA receptors, the gates studied in relation to synaptic density and learning.
The threonate form is studied for its ability to raise magnesium in cerebrospinal fluid, where most salts show little change.
In cell and animal models, magnesium L-threonate is studied for effects on oxidative stress within neurons.
For research use only. Mechanisms described reflect published preclinical and clinical literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
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FAQ
Common questions about Magnesium L-Threonate
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
Order with coverThird-party tested
An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.
